Where 10-bit really matters
Although graphic cards that support 10-bit per channel per pixel have been around for a few years, there is a big difference between cards that can just display 10-bit in 2D mode and those that can load 10-bit images quickly or provide 3D acceleration and 10-bit at the same time. A great example of where this really matters is mammography, where the slightest color variation in a digital breast scan could indicate the presence of a tumor. 10-bit precision delivers more information to the eye of the radiologist. But these dataset are large and need to load fast if they are going to be used by busy medical staff, instead of their regular hardcopy velum.

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